Donald Trump's special envoy Steve Witkoff and the US president's son-in-law Jared Kushner are heading to Pakistan for peace talks with Iran on Saturday morning, the White House has said, BBC reports.
"The Iranians want to talk," White House press secretary Karoline Leavitt said, adding that US Vice-President JD Vance was "on standby" to travel if the talks proved successful.
Iran's foreign ministry spokesman Esmail Baqaei said he and Foreign Minister Abbas Araghchi had arrived in Islamabad on Friday evening, and Araghchi would be meeting "Pakistani high-level officials".
He added that: "No meeting is planned to take place between Iran and the US. Iran's observations would be conveyed to Pakistan."
Ahead of Baqaei's comments, US Defence Secretary Pete Hegseth said Tehran had a chance to make a "good deal", stressing that "all they have to do is abandon a nuclear weapon and in meaningful and verifiable ways".
At Friday's news briefing, Hegseth also warned that Washington's continuing blockade of the Strait of Hormuz - a major oil shipping route - was "growing and going global".
The US and Israel began attacking Iran on 28 February, and Tehran subsequently restricted shipping through the Strait of Hormuz.
The moves by the warring sides have sent oil prices skyrocketing around the globe.
Speaking to reporters on Friday, Leavitt said Trump had decided to send Witkoff and Kushner to Islamabad "to hear the Iranians out", adding that US president is "always willing to give diplomacy a chance".
Leavitt added that "we've certainly seen some progress from the Iranian side in the last couple of days".