Iranian Supreme Leader Ayatollah Ali Khamenei rejected Donald Trump's demand for unconditional surrender on Wednesday, and the U.S. president said his patience had run out, though he gave no clue as to what his next step would be, Reuters reports.
Speaking to reporters outside the White House, Trump declined to say if he had made any decision on whether to join Israel's bombing campaign against arch-enemy Iran.
"I may do it. I may not do it. I mean, nobody knows what I'm going to do," he said.
Trump said Iranian officials had reached out about negotiations including a possible meeting at the White House but "it's very late to be talking," he said.
"Unconditional surrender, that means I've had it."
Asked for his response to Khamenei rejecting his demand to surrender, Trump said: "I say, good luck."
Iranians jammed highways out of the capital Tehran, a city of 10 million people, as residents sought sanctuary from intensified Israeli airstrikes.
In its latest bombing run, Israel said its air force destroyed Iran's police headquarters.
Israeli Prime Minister Benjamin Netanyahu, in a video released by his office on Wednesday evening, said Israel was "progressing step by step" towards eliminating threats posed by Iran's nuclear sites and ballistic missile arsenal.
"We control the skies over Tehran. We are striking with tremendous force at the regime of the ayatollahs. We are hitting the nuclear sites, the missiles, the headquarters, the symbols of the regime," Netanyahu said.
He also thanked Trump, "a great friend of the state of Israel", for standing by its side in the conflict, saying the two were in continuous contact.