The FBI is investigating an "act of targeted violence" after four people were killed in a shooting and fire at a Mormon church in Grand Blanc Township, Michigan, BBC reports.
The suspect, named as Thomas Jacob Sanford, was killed after officers "engaged in gunfire" with him in the church car park, police say.
Police told a news conference that the church had not yet been entirely cleared because of the extensive fire damage, and that some people remained unaccounted for.
US politicians have condemned the incident - the latest in a string of high-profile cases of armed violence that shocked the country.
US President Donald Trump has called the attack "horrendous", while former governor and presidential candidate Mitt Romney, a prominent Mormon politician, called for "praying for healing and comforting".