MI6 will be led by a woman for the first time in the foreign intelligence service's 116-year history,
BBC reports.
Blaise Metreweli, who joined the Secret Intelligence Service in 1999, will become the 18th chief of the organisation and take over from Sir Richard Moore later this year.
She is currently responsible for technology and innovation at the service and said she was "proud and honoured" to have been asked to lead.
Prime Minister Sir Keir Starmer called the appointment "historic" at a time "when the work of our intelligence services has never been more vital".
MI6 is tasked with gathering intelligence overseas to improve the UK's security, with its core aims being to stop terrorism, disrupt the activities of hostile states and bolster cyber-security.
Its chief, commonly referred to as "C", is the only publicly named member of the service.
Ms Metreweli, 47, is currently Director General "Q" - head of the crucial technology and innovation division that aims to keep the identities of secret agents secret, and come up with new ways to evade adversaries like China's biometric surveillance.
"MI6 plays a vital role - with MI5 and GCHQ - in keeping the British people safe and promoting UK interests overseas," she said.
"I look forward to continuing that work alongside the brave officers and agents of MI6 and our many international partners."
Ms Metreweli, who studied anthropology at the University of Cambridge, has previously held director level roles in MI5 - MI6's sister, domestic security agency - and spent most of her career working in the Middle East and Europe.
On the King's overseas and international birthday honours list in 2024, she received the Companion of the Order of St Michael and St George (CMG) for her services to British foreign policy.
